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Projects & Results

Personalized dietary therapies for treating inflammatory bowel disease

Project Details

Lead Researcher(s)

Levinus A. Dieleman

Co-Researcher(s)

Ammar Hassanzadeh Keshteli, David Wishart, Karen Madsen, Richard N. Fedorak, Roscia Valcheva

Funding Partners

Alberta Egg Producers, Al-Bio, ALMA, Alberta Milk

July 2012 - July 2015

The Challenge

Alberta has one of the highest rates of inflammatory bowel disease (IBD) in the world and costs the Canadian health-care system over $50,000/year/patient. Current treatments with anti-inflammatory and immunosuppressive medication can cause unwanted side-effects, and often surgery.

The Project

Use metabolomics to develop and monitor effective dietary therapies for IBD and develop Alberta-grown food product based IBD diet therapies to reduce relapse.

The Results

Dietary modifications that lower intake of inflammatory-type foods and increase anti-inflammatory foods can prevent colonic inflammation in clinical remission ulcerative colitis patients.

Grower Benefits

Canola oil helps prevent colonic inflammation in individuals suffering from IBD through an ‘anti-inflammatory’ diet, consisting of an increased consumption of omega-3 fatty acids.

Keywords:

Inflammatory bowel disease, IBD, Diet